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Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking Cessation

RecruitingPhase 4Ages 18 Years - anyAllOttawa Heart Institute Research Corporation
NCT06832085 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this vanguard trial is to test whether clients of Sun Life are willing to join in a quit smoking program that offers counselling and tobacco cessation products to all participants over a 12-month period. The study team will track the safety and usage of 3 types of cessation products as well as the effectiveness of a virtual pharmacy (i.e. cessation products delivered to participants directly from a pharmacy). The goal is to recruit a minimum of 150 participants for this Vanguard phase. The purpose of this study is to look at 3 approved smoking cessation products used in combination with counselling and virtual delivery of the smoking cessation products. The goal is to track product usage, safety, and adherence (how much of the products people use and how many counselling sessions they complete). Within the study there will also be an observational group who will not rece

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults (≥18 years) * Current cigarette smokers (more than 5 cigarettes per day) who are interested in reducing or quitting in the next 6 months. * Able to provide informed consent. * Living in Ontario, Canada Exclusion Criteria: * Contraindications to any of the study medications (NRT, cytisine, varenicline). * Actively using one of the study medications in the past 7 days. * Actively enrolled in another formal smoking cessation program. * Pregnant or breastfeeding individuals. * Unable to engage in follow-up for any reason (for example an acute mental illness, cognitive impairment, unable to speak English or French). * Other conditions deemed by the study team to interfere with participation or outcomes in the opinion of the study investigator (for example acutely unwell, life expectancy less than 1 year).
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What it tests

  • Nicotine Replacement Therapy (Nicotine patch plus NRT gum or lozenge)
  • Cytisine
  • Varenicline (Champix)
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Where

1 site
University of Ottawa Heart Institute
Ottawa, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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