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Soft Tissue Sarcoma: Motor Performance, Robotic Rehabilitation, Nutrition, and Quality of Life

RecruitingNAAges 18 Years - anyAllFondazione Policlinico Universitario Campus Bio-M…
NCT06873685 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Soft tissue sarcomas are a group of rare and heterogeneous tumors. Surgery is the mainstay of treatment and microscopic negative margins need to be achieved to improve disease local control. We designed this prospective study to evaluate the main features of motor impairment and the impact of tailored robotic rehabilitation techniques in patients treated for localized soft tissue sarcoma (surgery alone, or surgery + radiation or radiochemotherapy). Specific patients' motor strategies will be quantitatively measured through a biomechanical assessment, including the analysis of joint kinematics, and muscle activity timing patterns. Considering the influence of motor impairment after demolitive surgery, a major interest of this study will be focused on nutrition and Quality of life which will be prospectively evaluated by specific questionnaires at different time points.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. patient with primary and localized STS who is a candidate for limb-sparing surgery or retroperitoneal multivisceral resection (including partial or complete resection of the iliopsoas muscle with functional loss and potential femoral nerve involvement) with curative intent; 2. age 18 years or older. Exclusion Criteria: 1. recurrent tumors; 2. metastatic disease; 3. candidate for palliative and non-radical surgery; 4. refusal to sign informed consent; 5. Pregnant or breastfeeding women at the time of screening.
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What it tests

  • Rehabilitation
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Where

3 sites
Fondazione Policlinico Universitario Campus Bio-Medico
Rome, Italy
Fondazione Don Carlo Gnocchi ONLUS
Roma, Italy
Istituto Nazionale Tumori-IRCCS-Fondazione G.Pascale
Naples, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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