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Clinical Evaluation of New Biomarkers for Ischemic Cerebrovascular Disease

Recruitingn/aAges 18 Years - 90 YearsAllTongji Hospital
NCT06890702 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this single-center prospective observational study is to identify and evaluate new biomarkers for ischemic cerebrovascular disease (ICVD) to aid in early diagnosis, individualized treatment planning, and prognosis prediction in affected patients. The main questions it aims to answer are: Can specific biomarkers help in identifying high-risk individuals before disease onset? Can these biomarkers predict disease progression and treatment response? Researchers will compare patients diagnosed with ICVD and healthy controls from a medical check-up center to assess differences in biomarker expression and their clinical significance. Participants will: Provide blood, cerebrospinal fluid, urine, and stool samples for biomarker analysis. Undergo clinical imaging (CT, MRI, PET-CT) and functional assessments. Be followed up at 3, 6, 12, 24, 36, and 48 months for clinical outcomes an

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ischemic cerebrovascular disease has been proved by clinical symptoms and imaging examinations,including transient ischemic attack, cerebral ischemic stroke, steal syndrome, chronic cerebral hypoperfusion, ect al. * sex and age-matched healthy individuals Exclusion Criteria: * Brain CT or MRI showing cerebral hemorrhage (excluded ischemic stroke with hemorrhage transformation) * With severe systemic disease, are expected to survive \< 3 months * Patients will not able to provide continuous follow-up information
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What it tests

  • biomaker levels
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Where

2 sites
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,
Wuhan, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,
Wuhan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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