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The Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients

RecruitingPhase 4Ages 35 Years - 59 YearsAllUniversitas Indonesia
NCT06903546 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if propolis administration works to change the level of Low Density Lipoprotein (LDL) and High Density Lipoprotein cholesterol (HDL) in diabetic type 2 patients. The main questions it aims to answer are: \- Is giving 1 drops/ 10kg/ times, twice daily for 8 weeks will change the level of LDL and HDL level in diabetic type 2 patients compared to placebo? Researchers will compare propolis to a placebo (a look-alike substance that contains no drug) to see if propolis works to change LDL and HDL cholesterol level. Participants will: * Take propolis or a placebo, 2 times daily with given dose (1 drops/10 kg/times) every day for 2 months * Visit the sub-district health centre once every 2 weeks for checkups * Get their blood checked before and after intervention

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📋 Eligibility rules (as published)
Inclusion Criteria: * Controlled Diabetes Mellitus type 2 with HbA1c \<7.5% * BMI 23-35 kg/m2 * On anti-cholesterol therapy Exclusion Criteria: * Using injection therapy (insulin or GLP-1 RA) * History of bees product allergy * Active smoker * Consuming alcohol * Altered liver (ALT\>35 IU/L) and kidney (eGFR\<90 mL/min) function * Pregnant and breastfeeding women * History of cardiovascular disease (heart attack, stroke)
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What it tests

  • Propolis drops
  • Placebo
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Where

1 site
University of Indonesia Faculty of Biomedical Science
Jakarta, Indonesia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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