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Tamoxifen for Advanced Solid Pseudopapillary Tumor of the Pancreas

RecruitingPhase 2Ages 14 Years - 80 YearsAllFudan University
NCT06914674 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Tamoxifen for Solid Pseudopapillary Tumor of the Pancreas

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age 14-80 years. 2. Histologically confirmed advanced SPTP with ER/PR+. 3. Advanced disease: * Unresectable primary tumor or distant metastasis (liver, lung, peritoneum, etc.). * Recurrent or refractory after prior surgery/systemic therapy. 4. ≥1 measurable lesion. 5. ECOG performance status 0-2. 6. Life expectancy ≥1 month. 7. Able to comply with study visits and oral medication. Exclusion Criteria: 1. Non-SPTP pathology. 2. Active gastrointestinal inflammation/infection (e.g., pancreatitis). 3. Pregnancy/lactation. 4. Severe organ dysfunction (renal, cardiac, hepatic, or pulmonary). 5. Uncontrolled comorbidities (e.g., CNS disorders, unstable angina). 6. Conditions compromising patient safety or data integrity.
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What it tests

  • Tamoxifen 20 mg
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Where

1 site
Shanghai Cancer Center
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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