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Neurological and Physiological Effects of Animal-assisted Therapy for Patients in a Minimally Conscious State

RecruitingNAAges 18 Years - anyAllUniversity of Basel
NCT06931665 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to explore the impact of Animal Assisted Therapy (AAT) on brain signal complexity in patients with minimally conscious state (MCS) by analyzing electroencephalogram (EEG) entropy. MCS patients typically exhibit reduced brain entropy compared to healthy individuals, indicating lower brain complexity. The study will assess whether AAT can enhance this complexity, which is crucial for understanding consciousness levels. Entropy, a measure of randomness in brain activity, will be used to evaluate AAT's effectiveness. In addition, electrocardiography (ECG), electrodermal activity (EDA) and behavioral measurements will also be collected.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Inpatients in one of the study sites * Acquired brain injury resulting from either traumatic or non-traumatic events * Diagnosis of MCS defined by CRS-R according to the Aspen criteria (Giacino, 2005) * Informed consent as documented by signature by the patient's legal representative * Physiologically stable * Aged 18 or over Exclusion Criteria: * Phobia or allergies to any of the involved animals * Medical contraindications: acute or chronic disease (e.g. chronic pain, hypertension, heart disease, renal disease, liver disease, diabetes) * Radical changes in medication (decision made with responsible physician)
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What it tests

  • Animal Assisted Occupational Therapy
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Where

2 sites
REHAB Basel
Basel, Switzerland
Service de Neurorééducation, Hopitaux Universitaires Genevois
Geneva, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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