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Effect of Trunk Flexion on Airway Defense in Parkinson's Disease

Recruitingn/aAges 18 Years - anyAllGeneral University Hospital, Prague
NCT06955377 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The main mechanisms of airway protection include a properly functioning swallowing process and a cough. Studies focusing on patients with Parkinson's disease (PD) have previously demonstrated impairments in both swallowing (dysphagia) and coughing (dystussia). Aspiration pneumonia is the leading cause of death in individuals with PD. Swallowing function is directly related to body posture. Postural abnormalities (PA) are a common symptom of PD and significantly contribute to patient disability, affect respiratory function, and reduce quality of life. Previous research has shown that more than 20% of PD patients suffer from some form of PA. Most PD patients with a forward trunk flexion angle greater than 30 degrees report specific difficulties, such as dysphagia. A link has previously been demonstrated between postural abnormalities associated with flexed posture and restrictive ventila

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of Parkinson' s disease * Age ≥ 18 years Exclusion Criteria: * Unreliable performance of MIP, MEP, or grip strength measurements, for example, due to cognitive deficits (assessed by the researcher) * Inadequate lip seal * Significant deformities of the dominant hand that could affect the accuracy of grip strength measurements * Other severe neurological diseases apart from PD * History of unstable cardiovascular disease * Severe pulmonary disease
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What it tests

  • Not listed
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Where

1 site
General University Hospital
Prague, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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