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Predicting Psychotic Relapse Using Speech-Based Early Detection

Recruitingn/aAges 16 Years - anyAllDouglas Mental Health University Institute
NCT06978894 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse prediction

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age must be 16 years and older * Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions * Fluency in English or French * Must be currently receiving treatment through an EPI program Exclusion Criteria: * Severe comorbid speech or language disorders (e.g., aphasia) * Primary diagnosis of non-psychotic disorders * Inability to provide consent or complete assessments
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What it tests

  • Not listed
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Where

3 sites
Robarts Research Institute
London, Canada
Douglas Mental Health University Institute
Montreal, Canada
Vitam
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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