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A Study of Treatment-Related Toxicities and Quality of Life After Local Therapy in Chinese Breast Cancer Patients

Recruitingn/aAges 18 Years - anyFemaleFangYi
NCT07010939 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study, called PERSEVERE, examines how local treatment for early breast cancer affects people's health and daily lives over time. People who join the study will have early-stage breast cancer and receive treatment such as surgery and other therapies that are used before or after surgery. The study does not include people with late-stage (metastatic) breast cancer. Researchers want to learn about short- and long-term side effects that can happen during or after treatment. These may include tiredness, trouble sleeping, emotional distress, pain, or changes in heart or lung function. The study also looks at how these effects impact participants' quality of life. Participants will be asked to complete surveys about how they feel. They will also have health checks, such as heart tests, lung function tests, and blood samples. Tissue samples from surgery will also be collected. The goal

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women aged 18 years or older * Diagnosed with stage I, II, or III invasive breast cancer confirmed by pathology or cytology * No signs of metastatic disease (cancer that has spread to other parts of the body) * Scheduled to receive local treatment, including: Surgery And/or neoadjuvant or adjuvant therapy such as chemotherapy, radiation, hormone therapy, or targeted therapy * Willing and able to complete health questionnaires and attend follow-up visits * Has given written informed consent to join the study Exclusion Criteria: * Have metastatic breast cancer or local recurrence * Have already received curative treatment (surgery, chemo, etc.) for the current breast cancer before joining the study * Are currently pregnant or breastfeeding * Have a history of another cancer within the past 5 years (except for non-melanoma skin cancer or in-situ cervical cancer) * Are unable to participate in the study due to mental, physical, or legal reasons (for example, under legal guardianship or imprisonment)
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What it tests

  • blood sampling
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Where

3 sites
National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, China
Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center
Shenzhen, China
Shanxi Cancer Hospital
Taiyuan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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