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โ† Trials
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Comparison of Cold and Hot Loop Resection Techniques for the Removal of Medium-sized Benign Colon Tumors

RecruitingNAAges 18 Years - 100 YearsAllPirogov Russian National Research Medical Universโ€ฆ
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In plain words

What the trial is, and whether it could suit you

Widespread introduction of high-resolution videocolonoscopy into clinical practice has led to an increase in the detection of epithelial lesions of the colon, a significant portion of which are small (\<10 mm) and miniature (โ‰ค5 mm) lesions. According to the literature, 15.6-27% of colon lesions 6-9 mm in size and 4.4-10% of those โ‰ค5 mm are high-risk lesions, i.e. they contain villous structures, foci of severe dysplasia or cancer. One of the methods for removing such lesions is the technique of cold loop polypectomy (CLP), i.e. mechanical removal of the polyp with a loop without the use of electric current. This method is common for colon lesions 4-9 mm in size. (For smaller lesions, a technically simple and effective method of removing them using biopsy forceps is most often used) Jung YS, Park JH, Kim HJ et al. Complete biopsy resection of diminutive polyps. Endoscopy 2013; 45: 1024-9)

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * A patient with one benign non-invasive epithelial formation of the colon of type Is and II, measuring 10-14 mm * Age โ‰ฅ 18 years. * Signed informed voluntary consent for colonoscopy and removal of formations using the methods under study. Exclusion Criteria: * Reasonable suspicion of severe dysplasia/cancer, including with submucosal invasion based on the results of preoperative assessment (NICE - 3; JNET - 2b and 3; Kudo - Vi and Vn). -. Colonic lesions less than 10 mm * Recurrent lesion. * Presence of widespread malignant tumour in any part of the colon.- Use of other methods of endoscopic removal of the lesion. * IBD. * Patient on haemodialysis * Uncorrectable coagulopathy (INR\> 1.5). * Refusal to participate in the study. * General contraindications to endoscopic examination.
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What it tests

  • Cold endoscopic mucosal resection
  • Hot endoscopic mucosal resection
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Where

1 site
Evgeny Gorbachev
Moscow, Russia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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