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Thermal Therapies in the Treatment of Muscle Injuries

RecruitingNAAges 18 Years - 40 YearsAllAspetar
NCT07045129 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Muscle strain injuries represent one of the most prevalent injuries in athletes. Despite this high injury prevalence, there is no evidence to support some of the currently used therapeutic strategies. Amongst them, thermal therapies and especially cryotherapy modalities (Ice, Cold water immersion, perfused garments) have been extensively used on soft tissue injuries to reduce pain perception and decrease inflammation. However, recent findings in humans and in animals have reported conflictual results on the effects of cold on muscle regeneration. On the other hand, recent studies in humans suggest that passive heat exposure can impact positively muscle protein synthesis, mitochondrial content and muscle torque in injured, immobilized and healthy participants. Furthermore, preliminary results from our group have shown a faster removal of muscle damages from the muscle and suggest a better

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participant reported a sudden event * Acute onset pain located on the posterior thigh and/or rectus femuris injury * Clinical diagnosis of an acute muscle injury defined as: Localized pain during palpation of the area, Increasing pain during isometric contraction, Localized pain during specific tests. * MRI confirmed acute muscle lesion grade 1 - 2 - 3 (Pollock et al., 2014) of hamstring muscles o rectus femuris * Available for physiotherapy treatment 4-5 days a week * MRI of the injury performed in Aspetar within 7 days from the injury * Available for follow-up * Compliant with heat or cold-water immersion Exclusion Criteria: * Chronic condition, diabetes, or immune compromised state * Neurological, cardiovascular, pulmonary, or muscular pathology * Pacemaker wearer * Metallic prosthesis * Skin infection * Under medication: anti-inflammatory treatment, pain killer drugs, fluoroquinolone antibiotics * Contraindication to MRI * Previous verified or suspected lower limb muscle injury for the same leg and the same muscle within the last 6 months * Chronic lower limb muscle problems on the same muscle * Grade 0 and 4 muscle injury determined by MRI (Pollock et al., 2014) * Do not have an intention to return to full sport activity * Do not want to receive one of the therapies / Noncompliance with heat or cold therapies * Contraindication to heat * Do not want to comply with follow-up * Pregnancy
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What it tests

  • Cold water immersion
  • Hot water immersion
  • Physiotherapy only
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Where

1 site
Aspetar Orthopaedic and Sports Medicine Hospital
Doha, Qatar
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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