Omega-3D: Omega-3 for Diet-Driven Health Disparities

Inclusion Criteria: * Age ≥ 18 years * BMI ≥ 18.5 kg/m2 * Self-identify as non-Hispanic African American or non-Hispanic European American * Ability and willingness to transport for regular clinic visits. * Ability and willingness to swallow study capsules. * Willingness to refrain from intentional weight loss * Willingness maintain usual physical activity levels and dietary intake throughout the trial. Exclusion Criteria: * Age \> 65 years * BMI ≥ 40 kg/m2 * Currently pregnant or breastfeeding. * Currently receiving treatment for cancer (excluding adjuvant therapies). * Consumption of DHA/EPA-rich fish 2 or more days a week (defined as \>0.5 g DHA or EPA/serving) * Has a history of atrial fibrillation. * Has been diagnosed with a significant psychiatric condition that might compromise adherence to study protocols, including eating disorders, schizophrenia, bipolar (manic phase), severe personality disorders, severe major depressive, severe anxiety disorders, and substance use disorders. * Have an allergy to the study oils. * Have received other investigational agents within the past 6 months. * Currently on a weight reducing diet or has lost \>5% body weight in the past 6 months. * Currently using GLP-1 * Currently using prescribed anticoagulants or have a blood clotting problem or disease that causes excessive bleeding or been told by a physician that you have an increased risk of serious bleeding * Currently using oral steroids * Perceivably unable or unwilling to use acetaminophen in place of aspirin (including low dose regimen), NSAIDS, or other COX-2 inhibitors. * Perceivably unable or unwilling to refrain from using anti- inflammatory supplements (including n-3 supplements). * Perceivably unable or unwilling to refrain from using montelukast-type of allergy medications. * Run-in failure