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Intensive Care Unit-acquired Heart Failure in Critically Ill: the ICU-HF Study

Recruitingn/aAges 18 Years - anyAllCharite University, Berlin, Germany
NCT07094425 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Critically ill patients in intensive care units (ICUs) are exposed to a wide range of complications that can affect long-term morbidity and mortality. Not only the initial diagnosis at the time of admission may lead to complications; the ICU stay itself can also be associated with specific disease patterns. One of the most frequent complications of intensive care treatment is the loss of skeletal muscle mass. Muscle atrophy can be detected in up to 17% of all critically ill ICU patients. This is accompanied by a neuromuscular organ dysfunction collectively referred to as Intensive Care Unit Acquired Weakness (ICUAW). Milder forms of ICUAW are present in up to 40% of all ICU patients, which corresponds to approximately 1.2 million individuals per year in Germany alone. These patients face a multitude of long-term complications and have an increased mortality risk that may persist for up

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📋 Eligibility rules (as published)
Inclusion Criteria: * Critically ill patients aged ≥ 18 years * Initiation of mechanical ventilation within the first 24 hours after ICU admission * Expected duration of ICU stay of at least 3 days Exclusion Criteria: * Language barriers * Expected death during ICU stay or planned transition to best supportive care * Known allergy to electrode gel * Ultrasound not technically feasible (e.g., due to extensive wounds, skin rash, or dressings) * Patients with a pacemaker or similar electronic devices for whom bioelectrical impedance analysis (BIA) is contraindicated * Patients with severe aortic valve stenosis
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What it tests

  • transthoracic echocardiography
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Where

2 sites
Medical University of Vienna
Vienna, Austria
Charité - Universitätsmedizin Berlin
Berlin, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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