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โ† Trials
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Virtual Biopsy of Prostate Cancer Using PSMA PET and AI

Recruitingn/aAges any - anyMaleUniversity Hospital of North Norway
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In plain words

What the trial is, and whether it could suit you

Prostate cancer is the most common type of cancer in Norwegian men, but many tumors are slow-growing and do not require treatment. Today, MRI is good at detecting suspicious lesions, yet it cannot reliably distinguish aggressive tumors from low-grade ones. As a result, many men undergo repeated invasive biopsies. New PET tracers targeting PSMA improve tumor localization and may correlate with cancer aggressiveness, offering potential for better assessment. This project aims to develop a method to predict Gleason Score non-invasively by applying machine learning to PET and MRI data. The work involves early static and dynamic PSMA PET imaging, tracer kinetic modelling, deep learning, and validation of PET-based measurements of PSMA internalization using ex-vivo cellular methods. If successful, the project could reduce the number of biopsies, improve diagnostic accuracy, offer full 3D ass

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * For patients who have undergone biopsies prior to PET: * Patients referred to clinical PET examination * For patients who have not had biopsies prior to PET: * Patients referred to urologist for suspected prostate cancer based on clinical symptoms or elevated PSA-levels Exclusion Criteria: * Prostatektomy * Body weight under 100 kg * MRI incompatible implants or other incompatibilities
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What it tests

  • Not listed
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Where

1 site
Universitetssykehuset Nord Norge, Tromsรธ
Tromsรธ, Norway
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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