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The Influence of Beetroot Powder at a Dose of 20 g on Blood Pressure, Microcirculation, and Biochemical Markers in Men With Arterial Hypertension.SVEKLA2025.

RecruitingNAAges 18 Years - 60 YearsMaleNational Medical Research Center for Therapy and …
NCT07270718 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Objective: to evaluate the effectiveness of using a food product, dry finely dispersed beetroot powder in a dose of 20 g, containing 800 mg of nitrate (NO3-), in relation to the regulation of blood pressure in men with hypertension who reached the target blood pressure level while taking optimal antihypertensive therapy. Characteristics of the study: randomized, open, and cross-sectional. Relevance of the study Currently, it is recognized that vasodilatory endothelial dysfunction due to impaired synthesis and bioavailability of endogenous nitric oxide (NO) is a characteristic change in patients with arterial hypertension (AH) and plays one of the key roles in the development and progression of this pathology. Nitrate (NO3-), contained in food products, the highest content of which is found in beetroot, is converted into NO in the body after consumption, which can have a positive effect

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📋 Eligibility rules (as published)
Inclusion Criteria: * A history of hypertension with achievement of the target blood pressure level according to the SMAD while taking regular AGT; * signing informed consent to participate in the study. Exclusion Criteria: * coronary heart disease, including angina pectoris and myocardial infarction; cerebrovascular disease, including acute cerebrovascular accident and transient ischemic attack; obliterating atherosclerosis of peripheral vessels, revascularization in any vascular basin; cardiomyopathy; secondary forms of hypertension; type 1 or 2 diabetes mellitus, impaired glucose tolerance; inflammatory bowel diseases; organ transplantation; oncological, mental illnesses; diffuse connective tissue diseases in the anamnesis; * BMI ≥30 kg/m2; * symptoms of heart failure; * acute infectious diseases at the time of inclusion in the study and within 1 month prior to inclusion in the study; * Exacerbation of chronic non-communicable diseases; * alcoholism, taking narcotic drugs; * allergic and undesirable reactions to foods containing beetroot and egg white in the anamnesis; * refusal to continue participating in the study
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What it tests

  • Plus SVEKLA
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Where

1 site
National Medical Research Center for Preventive Medicine
Moscow, Russia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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