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ICG Lymphography Changes Before and After Radiotherapy in Breast Cancer Patients

Recruitingn/aAges 18 Years - anyFemaleInah Kim
NCT07297927 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn how the lymphatic system changes before and after radiotherapy in female patients with breast cancer. The study aims to understand early lymphatic changes that may lead to breast-cancer-related lymphedema (BCRL) and to help identify patients who might benefit from early preventive rehabilitation. The main questions it aims to answer are: How does lymphatic flow and vessel function change after radiotherapy, as measured by indocyanine green (ICG) lymphography? Can early imaging changes on ICG lymphography predict later swelling or lymphedema symptoms in the arm? There is no comparison or treatment group, since all participants will receive radiotherapy as part of their standard breast cancer care. Participants will: Undergo ICG lymphography before radiotherapy and again within 4-6 weeks after completing radiotherapy Receive a small i

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female, ≥18 years old * Pathologically confirmed stage I-III breast cancer * Scheduled to receive postoperative radiotherapy (RT) Exclusion Criteria: * Previous or current lymphedema * Prior radiotherapy to the ipsilateral breast or axilla * Severe systemic diseases (heart, renal, hepatic failure) * Active infection * Pregnancy or lactation * Allergy to indocyanine green (ICG) or iodine-based contrast agents
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What it tests

  • Not listed
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Where

1 site
Dongtan Sacred Heart Hospital
Hwaseong-si, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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