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Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on Body Weight and Body Fat Loss, Appetite, and Gastrointestinal Appetite Hormones.

RecruitingNAAges 18 Years - 60 YearsFemaleUniversity of Glasgow
NCT07299942 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite and gastrointestinal appetite hormones. This will be a double-blind, randomised, controlled trial in which healthy females living with overweight and obesity will be randomly assigned to a beta-glucan or a cellulose (placebo) group (1:1 basis). The randomisation software will be used to generate a randomisation list. This list will be held by a person independent of the research team. During the 4-week intervention, participants will consume an energy and carbohydrate-restricted diet combined with 9 g/day of beta-glucan (beta-glucan group) or 9 g/day of cellulose (Placebo group). During the 4-week intervention, breakfasts and dinners will consist of energy-restrict

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy females living with overweight or obese (BMI of 25 - 39.9 kg/m2). * Age between 18 to 60 years. * Stable body weight for at least 3 months preceding the study. Exclusion Criteria: * Smokers * Irregular menstrual cycle * Exercising more than 75min a week * Pregnant or lactating * Food allergies * Vegan or vegetarian or follow any diet other than the typical Western diet. * Taking dietary supplement at the time of the study.
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What it tests

  • Beta-glucan addition to a restricted calorie of meal replacements and carbohydrate diet.
  • Cellulose (Placebo) addition to a restricted calorie of meal replacements and carbohydrate diet.
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Where

1 site
Human Nutrition, College of Medicine, Veterinary and Life Science,
Glasgow, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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