🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Power of Belief: Expectation-driven and Placebo Modulation of Empathic Pain

RecruitingNAAges 18 Years - 30 YearsAllUniversity of Electronic Science and Technology o…
NCT07367672 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This study investigates how belief and expectation influence empathic pain-the pain we feel when observing others in distress. Healthy adult participants will be randomly assigned to one of three groups: no-treatment control, placebo nasal spray, oxytocin-containing nasal spray. Participants in both the placebo and oxytocin conditions will be informed that they are receiving oxytocin, described as a potent agent for pain relief. During functional MRI scanning, all participants will view naturalistic pain-related videos and provide ratings of perceived subjective pain. The study aims to examine how cognitive beliefs and neuromodulatory interventions alter subjective pain experience and brain activity, including changes in brain network communication.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * (1) Healthy subjects without any past or present psychiatric or neurological disorders; (2) Healthy subjects without any current psychotherapeutic medication. Exclusion Criteria: * (1) Participant with any past or present psychiatric or neurological disorders; (2)Participant with any current psychotherapeutic medication.
💊

What it tests

  • Intranasal Oxytocin (OT) 24 IU
  • Intranasal placebo administration
📍

Where

2 sites
Weihua Zhao
Chengdu, China
University of Electronic Science and Technology of China
Chengdu, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy