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Diet Synergy in Muscle Protein Synthesis

RecruitingNAAges 19 Years - 40 YearsAllUniversity of Illinois at Urbana-Champaign
NCT07367854 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise, participants will ingest either 1 medium russet potato with skins and 2 ounce-equivalent lean ground beef combination (274 kcals, 19.3 g protein, 5 g fat, 37 g carbohydrates, and 4 g fiber), 2 slices of white bread and beef combination (262 kcals, 19.8 g protein, 6.8 g fat, 28 g carbohydrates, and 1.8 g fiber) or 2 ounce-equivalent beef (93% lean meat/7% fat; 110 kcals, 14.8 g protein, and 5 g fat). Repeated blood and muscle biopsies will be collected to determine whole body leucine kinetics, amino acid concentrations, anabolic signaling and myofibrillar protein synthesis rates during the trials.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 19-40 yrs * Pre-menopausal * Recreationally-active * Weight stable for prior 6 months Exclusion Criteria: * Age outside of range (20 - 35 yrs) * Pregnancy * Irregular menstrual cycles (i.e., \~21 day or \~35 day cycle) * Participation in previous research using L-\[1-13C\] leucine and L-\[ring-2H5\] phenylalanine * Participation in other ongoing research that interferes with this study (e.g., conflicting diet, activity interventions, etc.)
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What it tests

  • Resistance Exercise
  • Potato and Beef
  • Bread and Beef
  • Beef
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Where

2 sites
Louise Freer Hall
Urbana, United States
Louise Freer Hall
Urbana, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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