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Serratus Posterior Superior Intercostal Plane Block for Analgesia in Off-Pump Minimally Invasive CABG

RecruitingNAAges 18 Years - 75 YearsAllKartal Kosuyolu High Speciality Training and Rese…
NCT07412522 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Postoperative pain after cardiac surgery is commonly moderate to severe due to sternotomy, thoracotomy, internal mammary artery harvesting, and chest tube placement, and may contribute to adverse systemic and pulmonary outcomes if inadequately managed. Enhanced Recovery After Surgery (ERAS) protocols emphasize opioid-sparing strategies to reduce opioid-related side effects and complications. Ultrasound-guided fascial plane blocks have increasingly been incorporated into perioperative analgesia protocols for cardiac surgery. The serratus posterior superior intercostal plane block (SPSIPB), a recently described technique, provides wide dermatomal sensory coverage and may offer effective analgesia in thoracic and cardiac surgical procedures. This prospective, randomized controlled study aims to evaluate the analgesic efficacy of SPSIPB in adult patients undergoing off-pump minimally invasi

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18-75 years * ASA physical status II-III * Scheduled for elective off-pump minimally invasive coronary artery bypass grafting (CABG) surgery * Ability to understand and use the Numerical Rating Scale (NRS) * Ability to provide written informed consent Exclusion Criteria: * Refusal to participate in the study * Known allergy or contraindication to local anesthetics * Coagulation disorders or ongoing anticoagulant therapy incompatible with regional anesthesia * Infection at the block injection site * Severe hepatic or renal dysfunction * Chronic opioid use or opioid dependence * History of chronic pain syndromes * Severe pulmonary disease (e.g., advanced COPD) * Neurological or psychiatric disorders that may interfere with pain assessment * Emergency surgery * Conversion to on-pump CABG or sternotomy during surgery
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What it tests

  • Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
  • Bupivacaine
  • Ultrasound
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Where

1 site
Kosuyolu High Specialization Training and Research Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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