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Clinical Utility of ctDNA in the Treatment of Oligometastatic Disease

Recruitingn/aAges 18 Years - anyAllAarhus University Hospital
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In plain words

What the trial is, and whether it could suit you

This prospective observational study investigates the clinical utility of circulating tumor DNA (ctDNA) in patients with oligometastatic disease (OMD) undergoing definitive-intent local ablative treatment (LAT). The study aims to evaluate ctDNA as a prognostic and response biomarker before, during, and after LAT across cancer types and treatment modalities. Serial plasma samples and archival tumor tissue will be analyzed to assess ctDNA detection rates, elimination patterns, minimal residual disease, and association with recurrence, progression, and survival outcomes.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Metastatic spread from histopathological diagnosed solid cancer * Planned for LAT (local ablative therapy) for OMD (oligometastatic disease) * โ‰ฅ 18 years * Written and oral consent Exclusion Criteria: * Other cancer disease within 5 years * Conditions that will contraindicate blood samples
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What it tests

  • Not listed
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Where

1 site
Department of Oncology, Aarhus University Hospital
Aarhus N, Denmark
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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