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Analysis of Inflammatory Biomarker Changes in Dry Blood Spot Versus Venous Blood Samples

Recruitingn/aAges 18 Years - anyAllMcGill University Health Centre/Research Institutโ€ฆ
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to see whether dried blood spot (DBS) samples can measure inflammatory biomarkers as accurately as venous blood samples. Investigators will be measuring inflammatory biomarkers changes obtained in DBS compared with paired venous blood samples following a controlled physiological stressor (i.e. after a vaccine or other planned event that can cause a temporary rise in inflammation). These findings will help understand whether DBS can be a reliable alternative to traditional blood draws in future research and healthcare.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Men or women aged โ‰ฅ18 years, who are planning to receive a seasonal vaccine OR have a scheduled acute stressor\*. Exclusion Criteria: * Any infectious symptoms (fever, cough, rhinorrhea, sore throat, diarrhea, loss of smell or taste) within the previous 7 days * Any self-reported active/recent use of cocaine, injection drugs, or amphetamines * Acute worsening of a known chronic health condition within the previous 30 days (e.g., of IBD, COPD, asthma, rheumatologic disease) * Known severe allergy or intolerance to the planned vaccine * Contraindication to the vaccine received, if applicable \*List of possible scheduled acute stressors include: * Hard exercise (incl. 10km run or longer, high-intensity interval training, or comparable endurance activity) * Social event with moderate alcohol consumption * Planned change in medication dose and/or frequency of use * Onset of menstruation (day 1) * Other pre-planned stressors expected to elicit an inflammatory response
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What it tests

  • Venous blood sampling
  • Dried blood spot sampling
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Where

1 site
Research Institute of the McGill University Health Centre
Montreal, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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