Concomitant Use of Radiotherapy and Integrated Exercise - Lung Cancer

Inclusion Criteria: * Histological diagnosis of non-small cell lung cancer (NSCLC) at stage II-III (locally advanced), unresectable/inoperable. * Candidate for radical radiotherapy with concomitant chemotherapy, with or without maintenance Durvalumab. * ECOG performance status ≤2 (or Karnofsky index ≥60). * Ability to communicate adequately with the research team and to complete questionnaires and functional tests. * Signed written informed consent after receiving detailed information about the study. Exclusion Criteria: * Decompensated cardiorespiratory comorbidities that contraindicate moderate-intensity physical exercise: * New York Heart Association (NYHA) class III-IV congestive heart failure or unstable angina. * Recent myocardial infarction (\<6 months) or uncontrolled arrhythmias. * Very severe chronic obstructive pulmonary disease (COPD) GOLD IV with recent exacerbations, permanent home oxygen therapy, or severe pulmonary hypertension. * Severe physical or neurological limitations that prevent exercise. * Absolute medical contraindications to inspiratory muscle training: unresolved pneumothorax, recent thoracic surgery (\<4 weeks), or active hemoptysis. * Refusal or inability to understand/follow the program instructions (e.g., severe cognitive impairment, insurmountable language barrier).