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Cardiovascular Acoustics for Early Disease Detection

Recruitingn/aAges 18 Years - anyAllCambridge University Hospitals NHS Foundation Tru…
NCT07496775 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

There are many types of heart disease. Two of the most common causes are narrowings within the blood vessels that supply the heart (known as coronary artery disease), or valves within the heart becoming narrowed (stenosed) or leaky (regurgitation), known as heart valve disease. There are two main types of imaging used to test for these conditions. Coronary artery disease can be diagnosed by taking X-ray pictures of a dye when injected into the blood vessels. In some cases the dye is injected into the veins and a CT scanner is used (CT coronary angiography), in others the dye is injected via a tube placed in the artery (invasive coronary angiography). Valvular heart disease is normally diagnosed using an echocardiogram (ultrasound of the heart). In this study the investigators are looking for subtle changes in the sounds that come from the heart, which may allow heart disease to be dete

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participants aged ≥18 years * Able to provide written, informed consent * Has undergone angiography in the previous 6 months and scheduled to undergo transthoracic echocardiography, or has undergone transthoracic echocardiography in the previous 6 months and scheduled to undergo angiography, or is scheduled to undergo transthoracic echocardiography and angiography within 6 months. * Angiography and echocardiography performed within Cambridge University Hospitals NHS Foundation Trust. Exclusion Criteria: * Haemodynamic instability * STEMI or high risk NSTEMI * Anginal symptoms at rest * Heart failure symptoms with NYHA 4 * Cardiovascular related admission or event occurring between imaging studies * Uncontrolled symptomatic arrhythmia * Acute pulmonary embolism * Acute aortic dissection * Previous valve intervention * Suspected endocarditis
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What it tests

  • Not listed
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Where

1 site
Cambridge University NHS Foundation Trust
Cambridge, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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