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Creation of a Decision Aid for Coronary Anomalies

RecruitingNAAges 10 Years - 35 YearsAllVanderbilt University Medical Center
NCT07544979 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The coronary arteries supply blood to the heart muscle. Typically, the left coronary artery comes from the left side of the aorta and the right coronary artery comes from the right side. In some cases the coronary artery comes from the wrong side of the aorta. This is known as anomalous aortic origin of a coronary artery (AAOCA). In AAOCA, the major concern is the risk of sudden cardiac death (SCD). The risk of is significantly higher in left AAOCA (L-AAOCA) compared to right AAOCA (R-AAOCA). With the increased risk in L-AAOCA, surgery is recommended to "normalize" the coronary artery position. R-AAOCA has a low absolute risk of SCD. But the risk is higher than the general population. Patients, families, and clinicians must weigh the risks of surgery with the risks of observation. This leads to stress and anxiety around making the management choice. There is no "right" management choice.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients * English-speaking * 10-35 years of age * Diagnosis of R-AAOCA without evidence of myocardial ischemia Parents * English-speaking * Child 10-17 years of age * Diagnosis of R-AAOCA without evidence of myocardial ischemia Exclusion Criteria: * Patients * Other significant cardiac anomalies * Unwilling or unable to provide consent * Non-English Speaking Parents * Child with other significant cardiac anomalies * Unwilling or unable to provide consent * Non-English Speaking
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What it tests

  • Decision aid
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Where

5 sites
Boston Children's Hospital
Boston, United States
Children's Hospital of Philadelphia
Philadelphia, United States
Vanderbilt University Medical Center
Nashville, United States
Dell Children's Medical Center
Austin, United States
Texas Children's Hospital
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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