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An Observational Study, Called FINEXPLORER, to Learn More About How Well Finerenone Works in Adults in Spain With Chronic Kidney Disease (CKD) Linked to Type 2 Diabetes, by Looking at Changes in a CKD Risk Score

Recruitingn/aAges 18 Years - anyAllBayer
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In plain words

What the trial is, and whether it could suit you

This is a prospective observational study in which data from people with chronic kidney disease (CKD) associated with type 2 diabetes (T2D) who will be receiving finerenone are collected and analyzed. Chronic kidney disease (CKD) is common in people with type 2 diabetes. It can get worse over time and may lead to kidney failure and heart problems. Doctors often track kidney health using blood and urine tests, including the estimated glomerular filtration rate (eGFR) and the urine albumin-to-creatinine ratio (UACR). There are also tools that combine routine laboratory test results to estimate a person's risk of their kidney disease getting worse. One of these tools is called the Klinrisk model. The study drug, finerenone, is already approved for doctors to prescribe to patients with CKD associated with T2D and albumin in the urine. Finerenone works by blocking the mineralocorticoid rec

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients who sign the written informed consent to participate in the study. * Men or women aged โ‰ฅ18 years. * Patients with CKD associated with type 2 diabetes and albuminuria (UACR \>30 mg/g). * Patients initiated on finerenone in routine clinical practice, according to the Summary of Product Characteristics (SmPC), within the 2 months prior to inclusion. Exclusion Criteria: * eGFR \< 25 mL/min/1.73 mยฒ. * Severe hepatic impairment. * Clinical diagnosis of chronic heart failure with reduced ejection fraction (HFrEF) and persistent symptoms. * Confirmed significant non-diabetic renal disease, including clinically relevant renal artery stenosis. * Uncontrolled arterial hypertension (mean sitting systolic blood pressure \[SBP\] โ‰ฅ160 mmHg or diastolic blood pressure \[DBP\] โ‰ฅ100 mmHg at inclusion). * Concomitant therapy with eplerenone, spironolactone, any renin inhibitor, or a potassium-sparing diuretic that has not been discontinued at least 4 weeks prior to inclusion.
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What it tests

  • Finerenone (Kerendia, BAY94-8862)
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Where

1 site
Many locations
Many Locations, Spain
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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