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Natural Cervical Ripening to Prevent Pharmacological Induction of Labor - a Pilot Study.

RecruitingNAAges 18 Years - anyFemaleUniversity of Zurich
NCT07587632 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

As of today, around 25% of all vaginal births happen after induction of labor (IOL). The internal guidelines of the University Hospital Zurich currently recommend pregnant women with a non-insulin dependent gestational diabetes an IOL around term. One possibility to prevent an IOL and increase the chance for a spontaneous onset of birth is a ripening of the cervix by alternative methods in an outpatient setting. The primary objective of this study is to evaluate the effect of natural cervical ripening methods on the time interval between 37 weeks (beginning of the intervention) and the onset of spontaneous labor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Singleton gestation * Non-insulin dependent, dietetically managed gestational diabetes * Greater than or equal to 34 weeks. * Planned vaginal birth at the University Hospital of Zurich * Planned IOL for 40 weeks of gestation. * Communication in German and/or English language possible. Exclusion Criteria: * Pregnant women with multiple gestation * Fetal macrosomia \>95th percentile * Intrauterine growth restriction \<3rd percentile * Already in labor (regular contractions or premature rupture of membranes (PROM) * Patients scheduled for IOL before 40 weeks * Insulin-dependent diabetes * Planned cesarean section * Planned birth in an external hospital * Inability to follow the procedures e.g. due to language problems, psychological disorders
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What it tests

  • Membrane sweaping and Breast massage
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Where

1 site
University Hospital Zurich
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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