๐ฌIn plain words
What the trial is, and whether it could suit you
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.
Sign in to get the eligibility rules as simple questions to take to your doctor.
๐ Eligibility rules (as published)
Inclusion Criteria:
* Diagnosis of central post-stroke pain (CPSP) according to the International Association for the Study of Pain (IASP) criteria
* Clear history of stroke confirmed by cranial CT or MRI
* Pain occurring after stroke and distributed in body parts corresponding to central nervous system injury
* Pain with neuropathic characteristics (e.g., burning sensation, electric shock sensation, needle prick sensation)
* Pain not explained by other causes
* Age โฅ 18 years
* Pain duration โฅ 3 months
* Baseline pain Numerical Rating Scale (NRS) score โฅ 4 points
* Complete clinical data with follow-up time โฅ 6 months
Exclusion Criteria:
* History of chronic pain before stroke
* Severe cognitive impairment that prevents cooperation with pain assessment (Mini-Mental State Examination, MMSE \< 15 points)
* Contraindications to spinal cord stimulation (SCS), such as coagulation disorders, active infections, or mental diseases that prevent cooperation
* Malignant tumors or other severe organic diseases with expected survival \< 1 year
๐
What it tests
- stSCS+Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline)
- Gabapentin or Pregabalin (with optional Duloxetine or Amitriptyline)
Nanchong Central Hospital
Nanchong, China
๐ค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ always decide together with your own doctor.