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Comparison of M-TAPA and ESPB for Postoperative Pulmonary Function After Laparoscopic Cholecystectomy

RecruitingNAAges 18 Years - 70 YearsAllKayseri City Hospital
NCT07666646 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, randomized, controlled clinical trial aims to compare the effects of two ultrasound-guided fascial plane blocks, the Erector Spinae Plane Block (ESPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA), on postoperative pulmonary function and analgesic consumption in patients undergoing laparoscopic cholecystectomy. Laparoscopic cholecystectomy is one of the most frequently performed abdominal surgical procedures worldwide. Despite minimally invasive techniques, postoperative pain remains a significant clinical problem due to port-site trauma, pneumoperitoneum, diaphragmatic irritation, and visceral manipulation. Inadequate pain control may lead to impaired respiratory mechanics, reduced mobilization, delayed recovery, and an increased risk of postoperative pulmonary complications. Postoperative pulmonary dysfunction is a common conse

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18-70 years * American Society of Anesthesiologists (ASA) physical status I-III * Patients scheduled for elective laparoscopic cholecystectomy * Patients who provide written informed consent * Patients who are able to cooperate and perform pulmonary function tests (PFTs) Exclusion Criteria: * Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia * Infection at the planned block site * Known allergy to local anesthetic agents * Conversion to open surgery * Hemodynamic instability * Inability to cooperate with pulmonary function tests (PFTs) * Pre-existing severe pulmonary disease (e.g., severe chronic obstructive pulmonary disease or restrictive lung disease) * Chronic opioid use or opioid dependence * Pregnancy or breastfeeding * Active smokers * Body mass index (BMI) \> 35 kg/m²
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What it tests

  • Modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA)
  • Erector spinae plane block (ESPB)
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Where

1 site
Kayseri City Hospital
Kayseri, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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