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Acute Effects of MCT Formulations on Beta-Hydroxybutyrate Response, Lipid Profile, and Glucose Levels in Healthy Adults

RecruitingNAAges 18 Years - 40 YearsAllUniversity of Milan
NCT07718048 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate the effects of medium-chain triglycerides (MCTs), delivered in different formulations, on beta-hydroxybutyrate response (as a marker of ketone body production), lipid metabolism, and glucose responses in healthy adults. The main questions it aims to answer are: Do MCTs influence beta-hydroxybutyrate responses, lipid metabolism, and glucose responses differently compared to long-chain triglycerides (LCTs)? Do different types of MCTs (natural sources containing C8 to C12 versus synthetic formulations containing only C8 and C10) lead to different beta-hydroxybutyrate, lipid, and glucose responses? Does the form in which MCTs are consumed (e.g., powders or incorporated into foods) influence beta-hydroxybutyrate production, lipid metabolism, and glucose responses? Researchers will compare five different lipid formulations to evaluate their e

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy adult participants * Age between 18 and 40 years * Ability to understand the study procedures and provide informed consent Exclusion Criteria: * Alterations in glucose or lipid metabolism * Diseases requiring the use of medications that affect glucose or lipid metabolism * Reported or diagnosed malabsorption conditions * Pregnancy or breastfeeding
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What it tests

  • MCT Beverage
  • LCT Beverage
  • Synthetic MCT Powder
  • Natural MCT Powder
  • MCT Biscuit
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Where

1 site
International Center for the Assessment of Nutritional Status and the development of Dietary Intervention Strategies (ICANS-DIS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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