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Periodontitis on Gingival Crevicular Fluid Metobolomics

Recruitingn/aAges 18 Years - 70 YearsAllUniversity of Catania
NCT07739732 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This cross-sectional observational study will compare the gingival crevicular fluid metabolomic profile of 30 adults with periodontitis and 30 periodontally healthy adults. Participants will undergo a periodontal examination and gingival crevicular fluid collection during a single study visit. Targeted metabolomic analysis will be used to identify differences between the two groups and associations with periodontal clinical parameters.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 70 years. 2. Ability to understand the study procedures and provide written informed consent. 3. For the periodontitis group: diagnosis of periodontitis according to the 2018 classification of periodontal diseases. 4. For the healthy control group: periodontal health according to the 2018 classification, with no current diagnosis or history of periodontitis. Exclusion Criteria: 1. Periodontal treatment during the previous 6 months. 2. Use of antibiotics, non-steroidal anti-inflammatory drugs, or immunosuppressive agents during the previous 6 months. 3. Pregnancy.
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What it tests

  • Periodontal probing depth
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Where

1 site
AOU Policlinico G. Rodolico
Catania, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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