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Unilateral and Bilateral Resistance Training in Hypertension

RecruitingNAAges 40 Years - 75 YearsAllHacettepe University
NCT07751445 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Hypertension is associated with autonomic nervous system dysfunction, reduced muscle strength, and impaired functional capacity, all of which contribute to increased cardiovascular risk and decreased quality of life. Resistance training is recommended as a non-pharmacological intervention for hypertension; however, it remains unclear whether unilateral and bilateral resistance training produce different physiological adaptations, particularly regarding cardiac autonomic function. This randomized controlled trial aims to compare the effects of unilateral and bilateral resistance training on heart rate variability (HRV), muscle strength, and functional capacity in adults with hypertension. Eligible participants aged 40-75 years with a confirmed diagnosis of hypertension will be randomly allocated to one of three groups: a unilateral resistance training group, a bilateral resistance traini

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 40 to 75 years. * Physician-confirmed diagnosis of hypertension. * Medically stable and able to safely participate in a supervised resistance training program. * Able to understand the study procedures and provide written informed consent. Exclusion Criteria: * Presence of cardiovascular diseases other than hypertension. * Neurological disorders. * Psychiatric disorders. * Orthopedic conditions limiting participation in resistance exercise. * Any other systemic disease that may interfere with study participation. * Cognitive impairment or psychological conditions preventing completion of the assessments. * History of recent surgery or medical conditions contraindicating exercise. * Inability or unwillingness to comply with the study protocol.
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What it tests

  • Unilateral Resistance Training
  • Bilateral Resistance Training
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Where

1 site
Munzur University Faculty of Health Sciences
Tunceli, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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