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โ† Trials
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A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity

RecruitingPhase 1Ages 18 Years - 55 YearsAllNovo Nordisk A/S
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In plain words

What the trial is, and whether it could suit you

The purpose of the study is to find out if NNC0721-8060 is safe and how it works in people living with overweight or obesity.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Male or female (sex at birth). * Age 18-55 years (both inclusive) at the time of signing informed consent. * Body Mass Index (BMI) 27.0-34.9 kilograms per square metre (kg/m\^2) (both inclusive) at screening, with overweight due to excess adipose tissue as judged by the investigator. * Considered eligible based on medical history, physical examination, vital signs, electrocardiogram and clinical laboratory tests at screening, as judged by the investigator. Exclusion Criteria: * Known or suspected hypersensitivity to study intervention(s) or related products. * Previous randomisation in this study. * History of allergies (with the exception of seasonal allergies) or history of anaphylactic reactions. * Female who is pregnant, breastfeeding, intends to become pregnant, or is of childbearing potential and not using adequate contraception. * Current participation (signed informed consent) in any other interventional clinical study. * Exposure to an investigational medicinal product within 30 days or five half-lives of that product (whichever is longer) before screening. * Any disorder, unwillingness or inability which, in the investigator's opinion, might jeopardise participant safety or compliance with the protocol. * Glycated haemoglobin (HbA1c) greater than or equal to (โ‰ฅ) 6.5 percentage (%) (48 millimoles per mole \[mmol/mol\]) at screening.
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What it tests

  • NNC0721-8060
  • Semaglutide
  • Placebo
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Where

2 sites
ICON Early Phase Services, LLC
Lenexa, United States
ICON
San Antonio, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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