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Deep Subgluteal Block vs PENG Combined With LFCN Block for Analgesia After Hip Arthroplasty

RecruitingNAAges 18 Years - 80 YearsAllMedipol University
NCT07770932 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized, prospective study aims to compare the clinical efficacy of ultrasound-guided Deep Subgluteal Block (DSGB) versus Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve (LFCN) block for postoperative analgesia management in patients undergoing hip arthroplasty. A total of 60 patients scheduled for hip arthroplasty under general anesthesia will be randomly allocated into two equal groups of 30: Group DSG and Group PENG+LFCN. Total local anesthetic volume (30 mL) and active drug dose (75 mg bupivacaine) will be standardized across both groups to ensure rigorous blinding and high methodological quality. The primary outcome of the study is to compare total postoperative opioid (fentanyl) consumption within the first 24 hours. Secondary outcomes include postoperative pain scores evaluated via the Numerical Rating Scale (NRS) at rest and during mo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients scheduled for elective total or partial hip arthroplasty under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Aged between 18 and 80 years * Able to understand the study procedures, give voluntary written informed consent, and operate a patient-controlled analgesia (PCA) device Exclusion Criteria: * Patient refusal or inability to provide informed consent * Pre-existing peripheral neuropathy, cognitive impairment, or psychiatric disorders * History of significant severe renal or hepatic failure * Allergy or hypersensitivity to amide-type local anesthetics or opioids * Infection, severe anatomic distortion, or previous surgery at the proposed block injection sites * History of substance abuse or chronic opioid use (defined as daily opioid use for \> 3 months prior to surgery)
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What it tests

  • 0.25% Bupivacaine for Deep Subgluteal Block
  • 0.25% and 0.125% Bupivacaine for PENG+LFCN Block
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Where

1 site
Medipol Mega University Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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