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Short-term Spinal Stimulation Effects in Cerebral Palsy

RecruitingNAAges 4 Years - 65 YearsAllUniversity of Washington
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In plain words

What the trial is, and whether it could suit you

This research study will examine the acute effects of non-invasive spinal stimulation on spasticity and walking in individuals with cerebral palsy. The hypothesis is that walking with spinal stimulation will lead to greater reductions in spasticity than walking without spinal stimulation. Additionally, it is hypothesized that the average step length and Gait Deviation Index will be higher while walking with spinal stimulation compared to walking without spinal stimulation.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Individuals who: * have a diagnosis of spastic cerebral palsy or high likelihood of CP diagnosis * are 4-65 years of age * have spasticity in lower-extremity muscles * are at a functional Gross Motor Function Classification System (GMFCS) Level I-III * can walk for at least 10 minutes with/without support * can understand and follow simple directions * have a stable medical condition, as reported by the caregiver/parent Exclusion Criteria: Individuals who: * who have had lower-extremity surgery or injury in the prior 12 months * have had botulinum toxin injections in the prior 3 months * have had selective dorsal rhizotomy (SDR) in the past * have uncontrolled seizures * have significant cardiovascular or musculoskeletal disease that would prevent full participation * are dependent on ventilation support * have implanted stimulator (e.g. epidural stimulator, vagus nerve stimulator, pacemaker, cochlear implant, etc) or drug delivery device (e.g. baclofen pump) * have established osteoporosis and taking medication for osteoporosis treatment. * have rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.) * have active cancer * have received stem cell injections into the spinal cord
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What it tests

  • Spinal Stimulation
  • Treadmill Walking
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Where

1 site
University of Washington
Seattle, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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