🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling

Recruitingn/aAges 18 Years - 45 YearsAllAristotle University Of Thessaloniki
NCT07846163 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers Magnetoencephalography (OPM-MEG). The study evaluates brain activity dynamics at rest and during controlled movement-evoked pain. Additionally, it explores the relationship between cortical processing markers and multidimensional biopsychosocial profiles (including pain intensity, kinesiophobia, catastrophizing, sleep quality, and functional disability) and gait adaptaions in adults with CLBP aged 18 to 45 compared to healthy pain-free controls.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria (Group of Chronic Low Back Pain Patients): * 18-45 years old * Non-specific low back pain * Duration of pain \> 3 months * Positive SLUMP test Inclusion Criteria (Group of Healthy Control Participants): * 18-45 years old * Healthy/ free of pain Exclusion Criteria (Common for both groups): * History of spinal injury * History of cancer * Bone metabolic diseases * Inflammatory conditions (spondyloarthritis or systemic inflammatory diseases) * Spondylolistethis * Presence of neurological deficits suggesting active nerve root compression/radiculopathy (pathological of tendon reflexes, sensitivity and muscle strength) * Diagnosed neurodegenerative/neurological disorders or epilepsy * Psychiatric disorders * High irritability, according to Severity, Irritability, Nature, Stage, and Stability- SINSS pain assessment tool. * Claustrophobia due to the measurement process inside the shielded room * Electrical/electronic implants(e.g. pacemakers), metallic surgical materials (e.g. plates, stent) and dental and orthodontic metallic materials (e.g. braces).
💊

What it tests

  • Not listed
📍

Where

1 site
Laboratory of Medical Physics and Digital Innovation, AUTH
Thessaloniki, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy