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A Clinical Trial of MK-8644 in Healthy Participants and Participants With Psoriasis (MK-8644-001)

RecruitingPhase 1Ages 18 Years - 65 YearsAllMerck Sharp & Dohme LLC
NCT07850310 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this trial is to learn about a trial medicine called MK-8644. This trial is the first time researchers will give MK-8644 to people. This trial will help researchers learn about the safety of MK-8644 and if participants tolerate it. Tolerate means participants will receive MK-8644 in the trial unless they need to stop it due to health problems.

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📋 Eligibility rules (as published)
Inclusion Criteria: The main inclusion criteria include but are not limited to the following: * Is in good health * Has a BMI between 18 and 36 kg/m\^2, inclusive Exclusion Criteria: The main exclusion criteria include but are not limited to the following: * Has a history of clinically significant endocrine, GI, cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases. * Has a history of cancer. * Has a history of significant multiple and/or severe allergies. * Has positive test(s) for hepatitis B surface antigen (HBsAg), hepatitis C antibodies, tuberculosis, or HIV.
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What it tests

  • MK-8644
  • Placebo for MK-8644
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Where

1 site
Nucleus Network ( Site 0001)
Melbourne, Australia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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