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โ† Trials
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Cooling During Inpatient Rehabilitation in Persons With MS

RecruitingNAAges 18 Years - anyAllKlinik Valens
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to shed light on the use of cooling during intensive active training sessions during a three-week multidisciplinary inpatient rehabilitation stay in persons with Multiple Sclerosis. The objectives of this study are: * to investigate the effects of one week of using a cooling vest during intensive active training sessions compared with one week of not using a cooling vest during inpatient rehabilitation on the state fatigue in persons with Multiple Sclerosis. * to investigate the effects of one week of using a cooling vest during intensive active training sessions compared with one week of not using a cooling vest during inpatient rehabilitation on the walking capacity, functional lower limb muscle strength, balance and cognition in persons with Multiple Sclerosis. * to investigate the effects of the three-week inpatient rehabilitation on the cardioresp

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * FSMC total score โ‰ฅ 43; * Adult age (โ‰ฅ 18 years); * A definite MS diagnosis according to the 2024 revised McDonald criteria with relapsing-remitting, primary or secondary progressive phenotypes; * Disease severity according to Expanded disability status scale (EDSS) score 3.0-6.0; * Subjective perceived heat sensitivity (Yes). Exclusion Criteria: * Inability to follow the study procedures (i.e. participant not fluent in oral and written German language); * Cognitive impairment (Montreal Cognitive Assessment, MoCA score \< 26); * Severe concomitant disease states (i.e. orthopaedic, cardiovascular, metabolic, psychiatric (e.g., substance abuse), other neurological disease states, other serious medical conditions) impairing the ability to participate; * Participation in another study; * Pregnant or lactating women; * Intention to become pregnant during this study; * Suspected non-compliance; * Previous enrolment into this study; * Sudden severe disease progression or falling sick (e.g. bacterial or viral infections) during the study; * Subjective perceived cold sensitivity (Yes).
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What it tests

  • Wearing a cooling vest during intensive, active training sessions
  • Control
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Where

1 site
Rehabilitation clinic Valens
Valens, Switzerland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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