🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Undenatured Type II Collagen for Knee Osteoarthritis Pain

RecruitingNAAges 31 Years - anyAllUniversidad Católica San Antonio de Murcia
NCT07870967 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This randomized, controlled, double-blind, three-arm parallel clinical trial will evaluate the efficacy and safety of undenatured type II collagen products on joint pain in adults diagnosed with knee osteoarthritis. Participants will be randomized to Nuvicol II (nuvicol® II), Nuvicol SII (nuvicol® S II), or placebo and will consume one capsule daily for 4 months. Pain, quality of life, knee muscle function, concomitant analgesic medication use, cartilage degradation biomarkers, safety laboratory variables, and adverse events will be assessed during follow-up.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age over 30 years. * Subjects diagnosed with osteoarthritis with functional grades I-III according to the modified American College of Rheumatology criteria. * Persistent knee pain associated with osteoarthritis with a baseline VAS pain assessment score of at least 30 mm. * Subjects must not have narcotic or steroidal anti-inflammatory drugs or immunosuppressants in their treatment. Exclusion Criteria: * Serious or terminal illnesses. * Allergy or hypersensitivity to any component of the product under study. * Vegan or vegetarian diet. * Current use of glucosamine, chondroitin sulfate, collagen, hyaluronic infiltrations, or any supplement indicated for joint health. * Chronic inflammatory diseases affecting the musculoskeletal system, including rheumatoid arthritis, gout, pseudogout, Paget disease, or chronic pain syndrome. * Body mass index above 32 kg/m2. * Participation in any other research during the last 3 months. * Pregnant, planning pregnancy during the study, lactating, or breastfeeding. * Biological childbearing potential without continuous effective contraception as determined by the investigator. * Inability to understand the research study.
💊

What it tests

  • Placebo
  • Nuvicol II
  • Nuvicol SII
📍

Where

1 site
UCAM HiTech - Unidad de Estudios Clínicos
Murcia, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy