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Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery.

RecruitingPhase 3Ages any - 18 YearsAllChildren's Cancer Hospital Egypt 57357
NCT07878156 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate the effects of ultrasound-guided versus blind greater occipital nerve block (GONB), with or without Dexmedetomidine as an adjuvant, in pediatric patients undergoing posterior fossa tumor excision under general anesthesia. The main questions it aims to answer are: * Does ultrasound-guided GONB improve hemodynamic stability compared with the blind technique? * Does adding dexmedetomidine to GONB affect intraoperative and postoperative opioid consumption, postoperative pain control, and the time to first rescue analgesia? Researchers will compare four groups to evaluate the effects of the nerve block technique and the addition of dexmedetomidine: Group A: Blind GONB using 0.25% bupivacaine. Group B: Blind GONB using 0.25% bupivacaine with dexmedetomidine (1 ฮผg/kg). Group C: Ultrasound-guided GONB using 0.25% bupivacaine. Group D: Ultrasound

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Pediatric patient undergoing elective posterior fossa tumor excision. * ASA physical status II-III. * Informed consent obtained from parents or legal guardians. Exclusion Criteria: * Allergy to study drugs (Bupivacaine - Dexmedetomidine) * Local infection at the site of injection. * Coagulopathy or use of anticoagulants. * Pre-existing neurologic deficits that interfere with postoperative pain assessment. * Developmental delay preventing appropriate pain evaluation. * Hemodynamic instability prior induction.
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What it tests

  • Bupivacaine 0.25%
  • Dexmedetomidine 1mcg/kg
  • Blind greater occipital nerve block
  • Ultrasound-guided greater occipital nerve block
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Where

1 site
Children's Cancer Hospital 57357
Cairo, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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