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Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear Surgeries

RecruitingPhase 2Ages 18 Years - 70 YearsAllMinia University
NCT07878533 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized, double-blind, controlled study will evaluate whether adding dexmedetomidine to bupivacaine in an ultrasound-guided greater auricular nerve block prolongs pain relief after middle ear surgery. Adults undergoing elective middle ear surgery under general anesthesia will receive the block before induction, either with bupivacaine alone or with bupivacaine plus dexmedetomidine. The main outcome is how long pain relief lasts after the block. Other outcomes include pain scores, opioid use, emergence agitation, hemodynamic changes, and side effects.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Inclusion Criteria: * Patients scheduled for elective middle ear surgery under general anesthesia * Aged 18-70 years * ASA physical status I or II * BMI ≤ 35 kg/m2 Exclusion Criteria: * Patient refusal * Known allergy to local anesthetics or dexmedetomidine * Coagulation disorders or anticoagulant therapy * Infection at the injection site * History of head and neck surgery * Significant cardiovascular disease (heart block, severe bradycardia, or uncontrolled hypertension) * Hepatic or renal impairment * Chronic opioid or analgesic use * Psychiatric disorders or inability to cooperate * Pregnancy or lactation
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What it tests

  • Bupivacaine
  • Dexmedetomidine
  • Normal saline
  • Ultrasound-guided greater auricular nerve block
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Where

1 site
Minia university hospital
Minya, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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