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Clinical Cohort of Memory Disorders

Recruitingn/aAges 19 Years - anyAllYonsei University
NCT07880275 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study is designed as a multicenter clinical cohort to collect and bank blood specimens linked to clinical and brain imaging data for biomarker discovery and validation in memory disorders. The protocol lists Severance Hospital, Gangnam Severance Hospital, and Yongin Severance Hospital as study sites. Planned enrollment is 1,550 participants: 1,500 adults aged 50 years or older and 50 healthy young adult controls aged 19-30 years. Participants are enrolled according to eligibility criteria and consent, irrespective of the specific medication received. Clinical information, cognitive assessments, and available brain magnetic resonance imaging (MRI) and positron emission tomography (PET) data will be collected to investigate diagnosis, disease severity, and clinical course. A total of 6 mL of research blood will be collected for banking, separated into plasma and buffy c

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📋 Eligibility rules (as published)
Inclusion criteria Memory disorder cohort: Adults of either sex aged 50 years or older. Healthy young adult controls: Adults of either sex aged 19-30 years. Participants must consent to participation. For patients with limited consent capacity and MMSE \<15, additional consent from a family representative is obtained. Exclusuion Criteria Memory disorder cohort: Uncontrolled acute or chronic infection, or another life-threatening systemic illness. Healthy young adult controls: 1. Any current self-reported medical, surgical, neurological, or psychiatric condition. 2. Self-reported history of liver, kidney, or heart disease. 3. Daily medication use. 4. Alcohol consumption on the day before blood collection. 5. Severe impact to the head within the past year, including a motor vehicle accident or fall. 6. Loss of consciousness for any reason within the past year.
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What it tests

  • Not listed
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Where

1 site
Yonsei University College of Medicine
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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