AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Extracorporeal Shockwave Therapy as an Additional Treatment for Spasticity Secondary to Spinal Cord Injury

RecruitingPhase 2Ages 18 Years - anyAllKessler Foundation
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

Spasticity is a common consequence of spinal cord injury and can have a profound impact on quality of life. The goal of this study is to learn if an intervention called focused extracorporeal shockwave therapy can enhance the effectiveness of injections received for spasticity, such as Botox. The main questions this study seeks to answer are whether shockwave therapy and toxin injection 1) can improve spasticity symptoms greater than toxin injection alone, and 2) change the structure of the injected muscles. Researchers will compare the group who receives both shockwave therapy and toxin injection to a group who receives only toxin injection. Participants will be asked to visit the clinic five times over the span of three months. The first three visits will occur on three consecutive weeks, during which participants will receive shockwave therapy or the sham therapy. The final two visits

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion criteria: 1. Women and men, age 18 years and older 2. Non-progressive SCI (complete or incomplete) with residual neurological deficits that occurred greater than 1 year prior to enrollment 3. Ankle flexor modified Ashworth scale (MAS) of between 1+ and 3, inclusive 4. No contraindication to f-ESWT, including current or recent infection at the treatment site and severe coagulopathies 5. No change in antispasmodic medications within the past 3 months or intended changes during the trial 6. currently being treated with BoNT in the plantar flexor muscles Exclusion criteria: 1. History of lower limb surgical procedures 2. Ankle contracture 3. Severe, inflammatory arthritic diseases 4. Thrombosis 5. Anticoagulant medication 6. Pregnancy 7. Cancer 8. Recent (12 months) local phenol/alcohol injection 9. MRI contraindications (e.g. claustrophobia, ferromagnetic implants or debris)
๐Ÿ’Š

What it tests

  • Focused extracorporeal shockwave therapy
  • Botulinum toxin
  • Sham
๐Ÿ“

Where

1 site
Kessler Foundation
West Orange, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy