A Study of 68Ga-FAPI Breast PET/MRI Scans in People With Breast Cancer

Inclusion Criteria: * Age ≥ 18 * ECOG Performance Status of ≤ 2 * Ability to review and signed informed consent * Histologically confirmed, newly diagnosed invasive breast cancer * Lymph node metastases (either histologically confirmed or radiographic evidence of lymph node metastases). * Planned to undergo SOC NAC prior to surgical resection as outlined in section 4.1 Exclusion Criteria: * Pregnancy or lactation. * Patients who cannot undergo PET/MRI scanning because of: * devices or implants that are not MRI safe * hypersensitivity or known allergy to gadolinium-based contrast agents * physical fitness not allowing scanning in prone for 30 minutes * weight limits (450 lb. weight limit) * Severe kidney disfunction (estimated GFR \< 30 ml/min/1.73 m2) (CKD-EPI (2021)) * Imaging features suspicious for concomitant in-situ cancer (LCIS/DCIS), such as nonbiopsied groups of microcalcifications * Distant metastases (contraindication for NAC)