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Multicenter Study for External Validation of the TB-NET Score

Recruitingn/aAges 18 Years - anyAllInstituto de Investigación Sanitaria de la Fundac…
NCT07903532 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a retrospective, observational, multicenter study aiming to externally validate the TB-NET Score in an independent cohort of patients with advanced well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) or lung carcinoids. The primary objective is to validate the prognostic value of the TB-NET Score for progression-free survival (PFS). Secondary objectives include the evaluation of overall survival (OS), objective response rate (ORR), grade 3-4 adverse events, biochemical and functional imaging correlates, and the potential additional prognostic value of tumor growth rate (TGR).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients with histologically confirmed well differentiated advanced GEP-NETs or Lung Carcinoids starting any line of systemic therapy. * Grade 1, 2 or 3 if well-differentiated morphology for GEP-NETs. Typical or Atypical Lung Carcinoids. * At least one target lesion. Exclusion Criteria: * Patients with Neuroendocrine Carcinomas. * Patients with no target lesions (according to RECIST 1.1 criteria).
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What it tests

  • Not listed
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Where

11 sites
Dana-Farber Cancer Institute
Boston, United States
Mallinckrodt Institute of Radiology
St Louis, United States
Hospital Sírio-Libanês
São Paulo, Brazil
Hôpital Beaujon
Clichy, France
Universitätsklinikum Erlangen
Erlangen, Germany
IRCCS Ospedale San Raffaele
Milan, Italy
University Hospital in Kraków
Krakow, Poland
Hospital Universitario Marqués de Valdecilla
Santander, Spain

…and 3 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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