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Two Bovine Xenografts in Lateral Window Sinus Augmentation With or Without Bone Marrow Blood

RecruitingNAAges 25 Years - 65 YearsAllUniversidad del Desarrollo
NCT07904065 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether adding a small amount of blood taken from the jawbone marrow improves new bone formation when two different bone graft materials are used in maxillary sinus lift surgery. The study includes adults aged 25 to 65 who need more bone height in the upper back jaw before receiving dental implants. The main questions it aims to answer are: * Does InterOss (a bovine bone graft material) form a similar amount of new living bone as Bio-Oss (a widely used bovine bone graft material)? * Does mixing either graft material with bone marrow blood from the lower jaw increase the amount of new living bone and the bone height gained? Researchers will compare four groups: Bio-Oss alone, InterOss alone, Bio-Oss mixed with jawbone marrow blood, and InterOss mixed with jawbone marrow blood. Each treated sinus is randomly assigned to one group. Patients tre

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📋 Eligibility rules (as published)
Inclusion Criteria: * Men and women aged 25 to 65 years. * Partially edentulous posterior maxilla requiring lateral window maxillary sinus floor augmentation prior to dental implant placement. * Residual alveolar bone height of 6 mm or less in the sinus area, measured on preoperative cone beam CT. * Non-smokers. * Good oral hygiene. * Good general health (ASA physical status I or II). * Adequate anatomical availability of mandibular medullary bone, assessed on cone beam CT. * Willing to participate and able to provide written informed consent. Exclusion Criteria: * Uncontrolled or untreated systemic disease. * Untreated psychiatric disorders. * Drug abuse. * Pre-existing acute or chronic sinus pathology. * Any blood disorder.
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What it tests

  • Deproteinized Bovine Bone Mineral (Bio-Oss)
  • Deproteinized Bovine Bone Mineral (InterOss)
  • Mandibular Bone Marrow Blood Aspiration
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Where

1 site
Universidad del Desarrollo (UDD)
Santiago, Chile
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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