🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Effect of Different Exercise Training Programs on Muscle Oxygenation in Individuals With Knee Osteoarthritis

RecruitingNAAges 45 Years - 65 YearsAllBahçeşehir University
NCT07904741 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Knee osteoarthritis can cause pain, reduced muscle strength, and difficulty with daily activities. Exercise is commonly used to manage knee osteoarthritis, but the effects of different exercise programs on muscle oxygenation are not fully understood. This study will compare three 6-week exercise programs in adults with knee osteoarthritis: aerobic exercise on a recumbent bicycle, lower-limb strengthening exercise, and a program combining aerobic and strengthening exercise. Participants will be randomly assigned to one of the three groups. Each group will attend three supervised exercise sessions weekly for 6 weeks. All participants will also receive a home stretching program. Participants will be assessed before the program, at weeks 3 and 6, and again at week 10, after a 4-week period without supervised exercise. The study will examine whether the exercise programs improve muscle oxyg

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age 45 to 65 years. * Body mass index (BMI) below 30 kg/m². * Physician-diagnosed knee osteoarthritis according to the American College of Rheumatology (ACR) criteria. * Bilateral knee osteoarthritis of Kellgren-Lawrence grade 2 or 3. * Willingness to participate and provide informed consent. Exclusion Criteria: * Orthopedic or rheumatologic disease of the lower extremities, or arterial or venous disease. * Uncontrolled hypertension, pulmonary disease, or diabetes. * Neurological disease. * Learning or cognitive impairment that may prevent participation. * Knee extension deficit. * Physical activity level above 600 MET-minutes/week, assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). * Treatment for knee osteoarthritis within the previous 6 months, including physical therapy or injection.
💊

What it tests

  • Recumbent-Cycle Aerobic Exercise
  • Lower-Limb Strengthening Exercise
  • Home Flexibility Exercise Program
📍

Where

1 site
İstanbul University Cerrahpaşa, Faculty of Health Science, Physiotherapy and Rehabilitation Lab
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy