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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Hepatocellular Carcinoma

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC NCT06553885Phase 21 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Enfortumab Vedotin Study of GV20-0251 in Participants With Solid Tumor Malignancies NCT07070518Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Shanghai GV20 Therapeutics ยท Tests: GV20-0251 Lenvatinib, Tislelizumab Combined With RALOX Regimen HAIC in Advanced Hepatocellular Carcinoma NCT05954897Phase 21 site๐Ÿ“ Guangzhou Guangdong Provincial People's Hospital ยท Tests: Lenvatinib, Tislelizumab Combined with RALOX Regimen HAIC Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT) NCT07312292Phase 21 site๐Ÿ“ Utrecht Niek Wijnen ยท Tests: Angiotensin II (Giaprezaยฎ), Yttrium-90 radioembolization Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC NCT06041477Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Oxaliplatin,calcium folinic acid, levofolinic acid, 5-FU, Concurrent Lenvatinib, Concurrent PD-1 antibody, Sequential Lโ€ฆ Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein ฮฒ-Catenin, The SAPHIRE Trial NCT06811116Phase 1, Phase 24 sites๐Ÿ“ Irvine๐Ÿ“ Orange๐Ÿ“ Portland National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Cabozantinib S-malate, Imaging Procedure, Sapanisertib Combination of TATE and PD-1 Inhibitor in Liver Cancer NCT03259867Phase 23 sites๐Ÿ“ Orange๐Ÿ“ Oklahoma City๐Ÿ“ Milwaukee Teclison Ltd. ยท Tests: Nivolumab Injectable Product, Trans-arterial tirapazamine embolization A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab PIN in Combination With Anti-PD1 in Previously Treated Primary Hepatocellular Carcinoma NCT07018518Phase 11 site๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: PIN +anti-PD1 Study of AU409 Capsule in Advanced Hepatocellular Carcinoma Patients Who Failed Standard Treatment NCT06374485Phase 11 site๐Ÿ“ Hong Kong Lee's Pharmaceutical Limited ยท Tests: AU409 Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial NCT05751343Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: TACE-HACI, plus atezolizumab-bevacizumab JMT106 Injection in the Treatment of Advanced Solid Tumors NCT07275073Phase 11 site๐Ÿ“ Zhejiang Shanghai JMT-Bio Inc. ยท Tests: JMT106 Injection Mts105 for Advanced Hepatocellular Carcinoma NCT06689540Phase 11 site๐Ÿ“ Beijing Shen Lin ยท Tests: MTS105 Becotatug Vedotin (MRG003) in Previously Treated Advanced Hepatocellular Carcinoma NCT07536789Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: MRG003 A Study of VRT106, Combined With Camrelizumab, and Apatinib for Advanced HCC NCT07589244Phase 2, Phase 31 site๐Ÿ“ Guangzhou Guangzhou Virotech Pharmaceutical Co., Ltd. ยท Tests: VRT106, VRT106 in combination with camrelizumab and apatinib, Investigator's Choice of Standard of Care An Open-Label, Phase I Clinical Trial of Super CAR-T With GPC3-Positive Advanced Hepatocellular Carcinoma NCT07493044Phase 11 site๐Ÿ“ Guangzhou Guangzhou FineImmune Biotechnology Co., LTD. ยท Tests: Super CAR-T Radioembolization as a Spearhead Treatment of Hepatocellular Carcinoma With Localized Portal Vein Tumor Thrombosis NCT06166576Phase 25 sites๐Ÿ“ Ilsan๐Ÿ“ Seongnam-si๐Ÿ“ Seoul Seoul National University Hospital ยท Tests: Ablative radioembolization HAIC in Combination with PD-1 Inhibitors and Lenvatinib for Intermediate and Advanced HCC After the Failure of Systemic Therapy Recommended by BCLC NCT06632093n/a1 site๐Ÿ“ Shenyang First Hospital of China Medical University ยท Tests: hepatic artery infusion chemotherapy, Lenvatinib + PD-1 monoclonal antibody A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer NCT06636435Phase 15 sites๐Ÿ“ Kashiwa๐Ÿ“ Yokohama๐Ÿ“ Niigata Chiome Bioscience Inc. ยท Tests: CBA-1205 Part 1, CBA-1205 Part 2, CBA-1205 Part 3, CBA-1205 Part 4, CBA-1205 Part 5 A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma NCT05440708Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Tvardi Therapeutics, Incorporated ยท Tests: TTI-101, Pembrolizumab, Atezolizumab, Bevacizumab Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors NCT04803318Phase 21 site๐Ÿ“ Guangzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: Combination of three inhibitors Trametinib, Everolimus and Lenvatinib Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies NCT03539822Phase 1, Phase 22 sites๐Ÿ“ Westwood๐Ÿ“ Pittsburgh Anwaar Saeed ยท Tests: Cabozantinib, Durvalumab, Tremelimumab Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC NCT05652920Phase 1, Phase 27 sites๐Ÿ“ Beijing๐Ÿ“ Changsha๐Ÿ“ Changchun OriCell Therapeutics Co., Ltd. ยท Tests: Ori-C101 PD-1 mRNA LNP Vaccine for Advanced Primary Hepatocellular Carcinoma. NCT07053072Phase 12 sites๐Ÿ“ Chengdu๐Ÿ“ Chengdu West China Hospital ยท Tests: Low Dose PD-1 mRNA LNP Vaccine, High dose PD-1 mRNA LNP vaccines Study Of B7H3 CAR-T Cells in Treating Advanced Liver Cancer NCT05323201Phase 1, Phase 21 site๐Ÿ“ Xuzhou The Affiliated Hospital of Xuzhou Medical University ยท Tests: fhB7H3.CAR-Ts, Fludarabine, Cyclophosphamide Infusion of PD1/PDL1/CTLA4 Inhibitors Via Hepatic Arterial for Immunotherapy of Hepatocellular Carcinoma NCT03949231Phase 31 site๐Ÿ“ Guanzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: PD1/PDL1 inhibitor Identification of an Immune Single Cell Transcriptomic Profile of Responder and Non-responder Hepatocellular Carcinoma Patients Treated With Immune-checkpoint Inhibitors NCT07273708n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial NCT07166406Phase 3139 sites๐Ÿ“ Berkeley๐Ÿ“ Cameron Park๐Ÿ“ Fremont NRG Oncology ยท Tests: Atezolizumab, Bevacizumab, Biospecimen Collection, Computed Tomography, Durvalumab Rituximab Combined With Prior Therapy in Advanced Hepatocellular Carcinoma: Efficacy & Safety Study NCT06301399Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Rituximab+PD-1 or PD-L1 inhibitors+targeted therapy Peg IFNฮฑ-2b Therapy for Unresectable Mid to Late Stage HBV-HCC NCT07769827NA1 site๐Ÿ“ Nanjing Jinling Hospital, China ยท Tests: Combined Peg IFNฮฑ-2b treatment group
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