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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Cystic Fibrosis (CF)

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy NCT06996951Phase 31 site๐Ÿ“ Indianapolis Indiana University ยท Tests: STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID, CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID Regional Monitoring of CF Lung Disease NCT06339593EARLY Phase 11 site๐Ÿ“ Cincinnati Children's Hospital Medical Center, Cincinnati ยท Tests: Airway-clearance vest, Hyperpolarized Xe129 Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/tezacaftor/ivacaftor in Urine After a Short Pause of Therapy NCT05818319NA1 site๐Ÿ“ Aarhus C University of Aarhus ยท Tests: 12 hours ETI pause, 36 hours ETI pause, 60 hours ETI pause Exercises' Effect on Muscle Strength, Aerobic Capacity and Respiratory Functions in Cystic Fibrosis NCT07508904NA1 site๐Ÿ“ Lahore Riphah International University ยท Tests: Arm Cycle Ergometry, Leg Cycle Ergometry Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis NCT07729787NA1 site๐Ÿ“ Multan Khurd Riphah International University ยท Tests: Autogenic Drainage, Mechanical Percussion Prevalence of Exercise-induced Ventilatory Limitation and Associated Factors in Patients With Cystic Fibrosis Receiving Elexacaftor-Tezacaftor-Ivacaftor NCT07314229NA1 site๐Ÿ“ Lille University Hospital, Lille ยท Tests: Measurement of resistance through forced oscillations and continuous measurement of ventilation and inspiratory capacitโ€ฆ Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study NCT05548283Phase 460 sites๐Ÿ“ Birmingham๐Ÿ“ Tucson๐Ÿ“ La Jolla Chris Goss ยท Tests: Beta-lactam antibiotic, Aminoglycoside Regional Phenotyping of CF and Non-CF Bronchiectasis NCT04793867n/a1 site๐Ÿ“ Cincinnati Children's Hospital Medical Center, Cincinnati ยท Tests: Xenon A Precision Medicine Approach to Assess Protein Function Loss and the Potential for CFTR Function Restoration in Cystic Fibrosis and Related Disorders NCT07889973n/a3 sites๐Ÿ“ Catania๐Ÿ“ Genova๐Ÿ“ Milan Istituto Giannina Gaslini Development and Validation of a Disease Specific PROM to Assess Abdominal Involvement in Patients With CF (CFAbd-Score) NCT03052283n/a2 sites๐Ÿ“ Brandenburg an der Havel๐Ÿ“ Brandenburg an der Havel Medizinische Hochschule Brandenburg Theodor Fontane ยท Tests: Questionnaire Patient Reported Outcome Measure (PROM) Population Pharmacokinetics of Elexacaftor-tezacaftor-ivacaftor in a Paediatric Population NCT07303621n/a1 site๐Ÿ“ Bron Hospices Civils de Lyon ยท Tests: There is no intervention as this is a prospective pharmacokinetics study. Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators on People With CF NCT05200429n/a2 sites๐Ÿ“ Vancouver๐Ÿ“ Vancouver University of British Columbia ยท Tests: Trikafta NCCR AntiResist:: New Approaches to Combat Antibiotic-resistant Bacteria NCT05017766n/a1 site๐Ÿ“ Basel University Hospital, Basel, Switzerland ยท Tests: analysis of antimicrobial resistance Personalized Mobile Health Platform to Promote Physical Activity in Adolescents and Young Adults With Cystic Fibrosis NCT06616857NA1 site๐Ÿ“ Jacksonville Nemours Children's Clinic ยท Tests: NUDGE, Education Epididymis Protein 4 and Pulmonary Function With Quality Improvement Protocol Among Cystic Fibrosis Patients NCT06915961n/a1 site๐Ÿ“ Cairo Ain Shams University Lung Transplant READY CF 2: CARING CF Ancillary RCT NCT06032273NA1 site๐Ÿ“ Seattle University of Washington ยท Tests: Investigator-designed lung transplant education website Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF) NCT05998629NA1 site๐Ÿ“ Hershey Milton S. Hershey Medical Center ยท Tests: a skin-interfaced colorimetric bifluidic sweat device with two synchronous channels, Standard of Care laboratory procedโ€ฆ Identifying the Causes and Risk Factors of Pulmonary Exacerbations in Cystic Fibrosis NCT06940531n/a18 sites๐Ÿ“ Manchester๐Ÿ“ Birmingham๐Ÿ“ Blackpool Alexander Horsley Modulate-CF: Cystic Fibrosis Transmembrane Regulator (CFTR) Biomarker Study to Evaluate the Rescue of Mutant CFTR in Patients With Cystic Fibrosis Treated With CFTR-modulators NCT04732910n/a4 sites๐Ÿ“ Berlin๐Ÿ“ Giessen๐Ÿ“ Hanover Charite University, Berlin, Germany ยท Tests: Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivโ€ฆ Diagnostic Value of Oropharyngeal Suction and Effect of Respiratory Physiotherapy on the Detection of Microorganisms in the Pediatric Patient NCT07903792NA1 site๐Ÿ“ Sabadell Corporacion Parc Tauli ยท Tests: Respiratory physiothperapy, Oropharyngeal suction, Oropharyngeal swab, Induced Sputum Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis NCT07569419EARLY Phase 11 site๐Ÿ“ Nottingham University of Nottingham ยท Tests: Linaclotide 290 micrograms, Lactose placebo pill Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs NCT01851642n/a1 site๐Ÿ“ Gainesville University of Florida ยท Tests: History and physical exam., Blood draw., Pulmonary function testing., Albuterol inhaler. IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study) NCT04294043Phase 110 sites๐Ÿ“ Birmingham๐Ÿ“ Denver๐Ÿ“ Baltimore Chris Goss ยท Tests: Gallium nitrate PERCE-MUCO: Perceptions and Expectations of People With Cystic Fibrosis Regarding a Change in Treatment NCT07885410n/a12 sites๐Ÿ“ Caen๐Ÿ“ Giens๐Ÿ“ Grenoble Fondation Ildys Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease NCT06985225n/a1 site๐Ÿ“ Kansas City University of Kansas Medical Center ยท Tests: Hyperpolarized 129 Xenon A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF) NCT06526923Phase 1, Phase 24 sites๐Ÿ“ Kansas City๐Ÿ“ Boston๐Ÿ“ New York Spirovant Sciences, Inc. ยท Tests: SP-101 and doxorubicin Cohort 1, SP-101 and doxorubicin Cohort 2 Study to Enable New Diagnostics for Pulmonary Microbes in People With CF NCT07312734n/a9 sites๐Ÿ“ La Jolla๐Ÿ“ Minneapolis๐Ÿ“ St Louis Chris Goss Novel Sensors and Artificial Intelligence for Detection of Acute Pulmonary Exacerbations in Cystic Fibrosis and Bronchiectasis NCT07289100n/a1 site๐Ÿ“ Cambridge Papworth Hospital NHS Foundation Trust ยท Tests: Non-Interventional Study Understanding Inflammation, InFection and Interventions in Severe Exacerbations of Cystic Fibrosis NCT07484607n/a6 sites๐Ÿ“ Cardiff๐Ÿ“ Exeter๐Ÿ“ Leeds Alexander Horsley Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet NCT07223255NA2 sites๐Ÿ“ Lebanon๐Ÿ“ Manchester Dartmouth-Hitchcock Medical Center ยท Tests: Mediterranean diet
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