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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Extensive Stage Lung Small Cell Carcinoma

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC NCT06497530Phase 21 site๐Ÿ“ Guangzhou Guangzhou Institute of Respiratory Disease ยท Tests: Serplulimab, Lurbinectedin, Carboplatin, Etoposide Liposomal Irinotecan and Apatinib in ES-SCLC NCT06749691Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Liposomal Irinotecan and Apatinib DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer NCT07545954Phase 11 site๐Ÿ“ St Louis Washington University School of Medicine ยท Tests: DSP-0390, Atezolizumab Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer NCT04919382Phase 25 sites๐Ÿ“ Chicago๐Ÿ“ Indianapolis๐Ÿ“ Iowa City Dwight Owen ยท Tests: Atezolizumab, Temozolomide Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES) NCT05068232Phase 22 sites๐Ÿ“ Chicago๐Ÿ“ Madison University of Chicago ยท Tests: Ablative Radiation, Durvalumab, Etoposide, Carboplatin Second-line Immunotherapy for ES-SCLC NCT06853678NA1 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Adebrelimab, Selinexor, Nab-paclitaxel Adebrelimab + Apatinib in SCLC Maintenance Therapy NCT06475209Phase 21 site๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: Adebrelimab combined with Apatinib A Prospective, Single-Arm, Single-Center Phase II Study Evaluating the Efficacy and Safety of Chidamide Combined With PD-L1 Inhibitor, Carboplatin, and Etoposide as First-Line Treatment in Patients With Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) NCT07373964Phase 21 site๐Ÿ“ Shenyang China Medical University, China ยท Tests: Chidamide Tablets๏ผ› PD-L1 Inhibitor (as per chosen drug's prescribing information)๏ผ›Carboplatin๏ผ› Etoposide Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation NCT06110572Phase 1, Phase 21 site๐Ÿ“ Nashville Vanderbilt-Ingram Cancer Center ยท Tests: Carboplatin, Atezolizumab, Etoposide, Total Body Irradiation, Hypofractionated Radiation Therapy A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC NCT07459634Phase 25 sites๐Ÿ“ Los Angeles๐Ÿ“ Jacksonville๐Ÿ“ Atlanta Jazz Pharmaceuticals ยท Tests: Lurbinectedin, Durvalumab Real-World Data on the Treatment of Lung Cancer Patients With the Immune-Checkpoint Inhibitor Tislelizumab NCT07510724n/a2 sites๐Ÿ“ Sankt Pรถlten๐Ÿ“ Frankfurt am Main Institut fรผr Klinische Krebsforschung IKF GmbH at Krankenhaโ€ฆ A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer NCT06437509Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, PD-1 monoclonal antibody A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) NCT06362252Phase 1, Phase 258 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Los Angeles Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan, Atezolizumab, Carboplatin A Study to Investigate Treatment Patterns and Effectiveness of Tislelizumab in European Patients With Resectable or Advanced Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC) NCT07652736n/a6 sites๐Ÿ“ Cรณrdoba๐Ÿ“ Jaรฉn๐Ÿ“ Lugo BeOne Medicines ยท Tests: Tislelizumab Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC NCT06223711Phase 25 sites๐Ÿ“ Augsburg๐Ÿ“ Erlangen๐Ÿ“ Regensburg Universitรคt des Saarlandes ยท Tests: Thoracic Radiochemotherapy, durvalumab, Stereotactic radiotherapy of further tumor locations, Chemotherapy Chemoimmunotherapy Plus Residual Lesion Irradiation for the Treatment of Extensive Stage Small-cell Lung Cancer NCT06514118n/a3 sites๐Ÿ“ Qingdao๐Ÿ“ Qingdao๐Ÿ“ Qingdao Qingdao Central Hospital ยท Tests: residual tumor irradiation Tempus Small Cell Lung Cancer Observational Study (Sculptor) NCT05257551n/a11 sites๐Ÿ“ Los Alamitos๐Ÿ“ Aurora๐Ÿ“ Peoria Tempus AI ยท Tests: Observation Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer NCT06758700Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: Teniposide administration Phase I Clinical Study of ฮฑ-PD-L1/DLL3 CAR-T in Patients With R/R SCLC NCT06348797Phase 11 site๐Ÿ“ Chengdu Sichuan University ยท Tests: ฮฑ-PD-L1/4-1BB DLL3 CAR-T (BHP01) The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer NCT07636200NA2 sites๐Ÿ“ Aurora๐Ÿ“ Boulder University of Colorado, Boulder ยท Tests: Written Exposure-Based Coping Intervention (EASE), Usual Care Control Condition A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment NCT07413042Phase 11 site๐Ÿ“ Beijing Peking University Cancer Hospital & Institute ยท Tests: [225Ac]Ac-DOTATATE A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) Small Extracellular Vesicle miRNAs as Predictive Biomarkers for Immunochemotherapy Efficacy in Extensive-stage Small Cell Lung Cancer NCT07070011n/a1 site๐Ÿ“ Shanghai Shanghai Chest Hospital of Shanghai Jiao Tong University ยท Tests: EC/EP + ICIs First Line Therapy for Extensive SCLC Patients, Treated with Chemo+Keytruda Followed by Keytuda+Trodelvy NCT06667167Phase 21 site๐Ÿ“ Jerusalem Nir Peled ยท Tests: Induction Carboplatin A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer NCT07155174Phase 270 sites๐Ÿ“ New Haven๐Ÿ“ Gainesville๐Ÿ“ Ocala AbbVie ยท Tests: ABBV-706, Atezolizumab, Etoposide, Carboplatin, Carboplatin Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) NCT05623319Phase 212 sites๐Ÿ“ Meldola๐Ÿ“ Monza๐Ÿ“ Pesaro Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRโ€ฆ ยท Tests: Pembrolizumab/Olaparib A Study of YL201 in Combination With Serplulimab in Participants With Treatment-naรฏve Extensive-stage Small Cell Lung Cancer NCT07739758Phase 32 sites๐Ÿ“ Guangzhou๐Ÿ“ Shenyang MediLink Therapeutics (Suzhou) Co., Ltd. ยท Tests: YL201, Serplulimab, Carboplatin, Etoposide Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease NCT07509034Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Autologous B7-H3 CAR T, Cyclophosphamide, Fludarabine A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung Cancer NCT07654400Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-M14D1, Atezolizumab A Study Comparing QLC5508 in Combination With QL2107 Versus Tislelizumab Plus Platinum-based Chemotherapy in Participants Wih Treatment-naรฏve Extensive-Stage Small Cell Lung Cancer NCT07802821Phase 31 site๐Ÿ“ Shanghai Qilu Pharmaceutical Co., Ltd. ยท Tests: QLC5508, QL2107, Tislelizumab, Carboplatin, Cisplatin
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